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Elevated TMAO levels have been linked to a number of diseases, including cardiovascular and neurological disorders, renal disease, metabolic syndrome, obesity, type 2 diabetes (T2D), non-alcoholic fatty liver disease (NAFLD), cancer, and severe COVID-19

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The result can be loose skin, reduced facial volume, visible stretch marks, thinning hair, and delayed healing from the increased physical activity that often accompanies a weight loss program

Many users report that pushing through the initial worsening phase leads to eventual improvement

Lingtak-Neander Chan, Pharm.D., is a board-certified nutrition support pharmacist, and a professor of pharmacy in the School of Pharmacy at the University of Washington, Seattle